The protocol form requires a non technical description of the research, a justification for the use of animals, a description of all procedures to be performed on animals, and precautions to be taken to guarantee humane care and treatment. In these cases, only a copy of the approved AUP from the affiliated institution and approval letter from its Animal Care Committee (ACC) is required. Please contact acc.coordinator@utoronto.ca to determine which type of AUP and/or additional documentation is required. Information Required for the Protocol. Accordingly, investigators should anticipate that the protocol may be reviewed by the general public. Anyone who wishes to use live animals in research or teaching at Western and its affiliates must disclose all procedures in an approved Animal Use Protocol (AUP). If you do not have access, please complete the New User & Request for Access to Topaz Form. Copies of the protocol form may be obtained from Animal Welfare Services (AWS). *Animals Observed With 'No Expected Impact': Given current knowledge of the behaviour of a particular species, the proposed study design, including access to or through sensitive areas (e.g., breeding sites), is unlikely to alter normal behaviour. 2. The LACC is responsible for the review and approval of teaching and research protocols to ensure that all animal use is in compliance with institutional, municipal, provincial, and federal regulations and guidelines. Overview 1.Describe briefly the purpose of the study, experimental procedures and manipulations of the animals, and the expected outcome in lay terms. © 2019 University of Toronto. Approach for Research Recovery & Adaptation, U of T Principles for Research Recovery & Adaptation, Guidance for the Recovery of Human Research During the COVID-19 Pandemic, COVID-19: Supplements for Tri-Agency Research Grants, CRIS Spotlight: COVID-19 Resources for Researchers, COVID-19 Response Resource: Online Sharing Platform, Graduate Studies Research Guidelines for Students, Canada Research Continuity Emergency Fund: Public Accountability & Transparency. Any instructor or Principal Investigator (PI) working with vertebrate species or cephalopods must submit an animal use protocol (AUP) to the appropriate Local Animal Care Committee (LACC) through the online system – My Research Animal Protocol (MRAP). This includes the timing and duration of specific behaviours (e.g., feeding, grooming, breeding) and interactions between conspecifics. d. In some cases, the original or revised protocol may be given to a subcommittee of the IACUC or an outside consultant(s) for further review. Activities involving interaction with animals not related to teaching or research. * IMPORTANT … Anyone planning to use animals in research or teaching at the University of Toronto (U of T), including those in the following roles. All University of Oregon faculty, students, or staff intending to use live or dead vertebrate animals in research or teaching must submit an application for the use of animals (protocol) to the IACUC. The use of animals on campus for social events/student club events, Third-party, animal-based activities held on campus (e.g., dog or horse club using campus facilities). Protocol or modification proposing the use of hamsters, gerbils, guinea pigs, rabbits, cats, dogs, farm animals, lizards, or other species regulated by the U.S. Department of Agriculture EXCEPT for protocols proposing the production of polyclonal antibodies by an approved contract facility using … Approval of AUPs - All vertebrate animals must be covered by an animal use protocol (AUP) approved by the Institutional Animal Care and Use Committee (IACUC) prior to acquisition and/or use of animals and throughout the entire period of animal use or maintenance. The protocol must be fully approved before an animal user may acquire, house or use animals. A U of T AUP is NOT required in the following circumstances. on the statement of non-discrimination. Who Can Be a Principal Investigator at U of T? 5.0 Person(s) Responsible for Procedure: Monte Matthews. 2.In order to perform its obligations in accordance with the NTU-IACUC Policies for Special Procedures, it needs a complete description of the proposed animal use and care. Protocols Before an investigator purchases/obtains and begins research involving vertebrate species of animal, an animal research protocol must be submitted for review and approval by the Institutional Animal Care and Use Committee (IACUC). Any animal research which is being conducted in a fully-affiliated institution within the Toronto Academic Health Science Network (TAHSN) and using U of T administered funding must be covered by an administrative U of T AUP. Submit Animal Use Protocols electronically through My Research (MR) Protocol instructions; Deadlines for submission DCM veterinary staff is available to review your Animal Use Protocols (AUPs) prior to submission. Thorough preparation of protocols facilitates the review process and reduces the chance of delay in initiating projects. Strictly observational studies on unconfined animals in the field do not require IACUC approval. This first review ensures that proposed housing, source of animals, drugs and dosages, and animal use procedures meet NIH Guide standards, comply with federal regulations and campus guidelines and policies. a. 4.0 Scope: All University faculty, researchers, staff and students who use or care for live vertebrate animals. In order to determine if an Animal Use Protocol (AUP) is required, first determine the scope and nature of the animal work. What Qualifies as an Eligible Expense for a Research Award? for Civil Rights. The investigator is notified of the receipt of the protocol and the assigned protocol’s number. It is recommended that protocols be submitted at least 90 days before the use of animals is to begin. Animal use protocol sample: overview of the procedure for mouse hybridoma production Hybridomas are permanent cell lines that secrete monoclonal antibodies. The protocol form requires a non technical description of the research, a justification for the use of animals, a description of all procedures to be performed on animals, and precautions to be taken to guarantee humane care and treatment. CCAC guidelines on: animal use protocol review (1997) The Canadian Council on Animal Care (CCAC) included Recommended Terms of Reference and Guidelines for Institutional Animal Care Committees in its Guide to the Care and Use of Experimental Animals, Vol. The Institutional Animal Care and Use Committee, or IACUC, is a committee appointed by the Chief Executive Officer of the institution. Retaliation is prohibited by Animal use protocols, amendments and renewals are prepared in the Topaz system. 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The … These changes will make it easier for you to identify which information is required in each section and should result in fewer reviewer questions moving forward. This includes the type(s) of species you plan to use, the types of activities that require animals use, and where the work will occur (e.g. The IACUC Animal Care and Use Protocol must be submitted by a Principal Investigator as the responsible party for conducting the proposed animal activities listed in the protocol application. Research Administration Policy & Guidelines, Partner with the Community / Industry for a Funding Application, Requirements for Research & Teaching Involving Humans or Animals, Export Controls & Controlled Goods Program, Financial Conflict of Interest Procedures: US Public Health Service & National Science Foundation, My Research Applications & Agreements (MRA). 3.0 Purpose: To describe basic information about the protocol review process. If you need additional space, attach pages. Contact information, related policies, and complaint procedures are listed The online protocol system will present a customized protocol form to the investigator based on the information provided by the investigator when beginning to complete a pr… An Animal Care and Use Protocol is a request made to the Institutional Animal Care and Use Committee (IACUC) to conduct a scientific experiment on live, vertebrate animals. IACUC approval must be obtained before initiating any research, testing or instructional project involving the use of live vertebrate animals (includes mammals, birds, fish, amphibians and reptiles). CCAC Requirement for Submitting an Animal Protocol >, CCAC Guidelines on the Care and Use of Wildlife >, CCAC Categories of Invasiveness in Animal Experiments >, Division of the Vice-President, Research & Innovation, General Inquiries: Animal Ethics & Compliance Unit. Veterinary staff is actively involved in the review of all AUPs and serve on the local Animal Care Committee. Please see the Researchers’ Guides in the Forms & Download section of this page for more information. There are 3 different Animal Use Protocols to choose from depending upon the type of animal research to be conducted. This includes but is not limited to the following. please answer all items completely. Title IX Coordinator, Office of Affirmative Action and Equal Opportunity, or to the Office Protocols are submitted to the IACUC through the IACUC’s online protocol system. b. Wildlife Laboratory Animal Use Protocol: use for wildlife field studies. The Topaz System can be accessed by web browsers (Internet Explorer, Firefox, Safari) from either a Mac or PC. Technical Problems or General Information: IACUC Office Anthony Yonkura: 292-4494 or Yonkura.1@osu.edu. b. Submit Animal Use Protocols electronically through My Research (MR) Obtain access to My Research; Protocol instructions; Deadlines for submission Before animals are acquired or used, all procedures must be subject to ethical review in accordance with federal guidelines (Canadian Council on Animal Care) and provincial legislation (Animals for Research Act- OMAFRA) on animal care and use. UO The PI is notified when a new protocol is submitted to the IACUC, irrespective of who submitted the protocol on behalf of the PI. handwritten forms will not be accepted. The eProtocol Animal Use Protocol (AUP) form has been updated to provide a clearer and more comprehensive format. If you experience problems, or have questions, please use the resources available to you, including the IACUC support staff or ULAR protocol consultant. Laboratory Animal Use Protocol: use for any laboratory-related species such as mice, rats, rabbits, guinea pigs, etc. Each animal use protocol (AUP) must be reviewed by full IACUC committee at least once every three years, and can be reviewed more frequently if the committee wishes. The affected forms are : Animal Use Protocol (AUP) applications (new and renewal) If you are still unsure as to whether you require an AUP, please contact General Inquiries: Animal Ethics & Compliance Unit as listed in the VPRI contact section below. Questions may be referred to the Approval of Animal Use Protocol The Office of Research Compliance and Biosafety, Animal Welfare Assurance Program staff receives all new AUPs and assigns an AUP number. Review of an Animal Care and Use Protocol by the IACUC is required regardless of animal use site (on campus or at UCSB Natural Reserve sites), funding source, species, or animal numbers. CITI Training instructions appear separately. faculty member, graduate student, post doc, etc.) What Happens If A Research Award is Overspent? As of 10 August 2018, all Animal Use Protocol (AUP) applications, amendments and annual reviews are to be created and submitted via ARFMS for the submission and review of IACUC-related submissions. At the University of Iowa, the review is conducted by the Institutional Animal Care and Use Committee (IACUC) via submission and review of Animal Protocols. read all instructions before preparing your animal use protocol, as forms that are incomplete will be returned. Animal Use Projects that will utilize live vertebrate animals must utilize them in accordance to protocols reviewed and approved by UW’s Institutional Animal Care and Use Committee (IACUC). The Committee can fully approve the protocol, give provisional approval subject to minor changes (in methods, for example), defer a vote until more information is provided, or request a meeting of the full committee. Title IX, other applicable laws, and policies. The Animal Use Protocol • If the scientist plans to use animals as part of the research, he or she must explain in a separate written document, called an animal use protocol, Why animals are needed to accomplish the aims, What procedures will be performed on the animals and How the animals will be housed and cared for throughout the project. There is great variation in the length, format, content, and use of these forms, and a form that serves one institution well may not necessarily prove successful at another institution. The Animal Use Protocol • If the scientist plans to use animals as part of the research, he or she must explain in a separate written document, called an animal use protocol, Whyanimals are needed to accomplish the aims, Whatprocedures will be performed on the animals and Howthe animals will be housed and cared for throughout the project. Veterinary review often helps to expedite the overall review process. at U of T or at another institution). religion, marital status, disability, veteran status, sexual orientation, gender identity, Most institutions have instituted an animal care and use protocol form that investigators are required to complete and submit to the IACUC. Animal Use Protocols Anyone who wishes to use live animals in research or teaching at Western University and its affliates must disclose all procedures in an approved Animal Use Protocol (AUP). at an external (host) institution, Sharing of animals with U of T (i.e., animals are transferred between U of T and a host institution as part of a study), U of T-administered funds are used for animal-based activities occurring at a host institution, The use of invertebrate animals (exception: cephalopods), The use of eggs, fetuses, embryos, and larvae in research or teaching (except fish and amphibian larvae that have reached a stage where survival can reasonably be expected), Cadavers of animals not killed specifically for the research or teaching in question, including the use of animals killed during established industry or commercial practices and animal tissues shared from other approved protocols, Animals that will only be observed in formal teaching and in research, that are not being held captive for these purposes, and where there is ‘no expected impact’*, Pets or display animals (e.g., fish) kept in offices or public areas unrelated to research or teaching. a. prohibits discrimination on the basis of race, color, sex, national or ethnic origin, age, Contact the IACUC office for a timetable of IACUC meetings and protocol submission deadlines. Animal Use Protocols Animal Use Protocols must be submitted on line using Topaz Enterprise—beginning January 1, 2010, all new submissions of animal protocols and all 36-month reviews, must be submitted in this format. The Institutional Animal Care and Use Committee. All rights reserved. this is a protocol for contract antibody services only. An AUP is required for all animal work (research and teaching) that will occur at the University of Toronto (U of T facilities) on campus or in the field (e.g. For teaching protocols, please see Pedagogical Merit Review for Animal Use for more information. Once these cells have been produced there are options for both in-vivo and in-vitro production of large volumes of the antibody. Investigators with questions regarding protocol preparation are encouraged to contact AWS. The committee ensures the study is ethical, that the animals are treated humanely, and that the appropriate species and minimum number of animals are being used. PROTOCOL Animal Use Protocol Berkeley Protocol # AUP-2020-05-13318 Date Printed: 05/22/2020 Personnel Information 1 Species 3 Are You Using? Following this preliminary review, the IACUC will contact the applicant by email or phone if clarifications or revisions are necessary (many of the protocols received require some clarification or revision). and gender expression in all programs, activities and employment practices as required by general instructions for animal use protocol form. Investigators with questions regarding protocol preparation are encouraged to contact AWS. the animal use protocol form must be typed. Review of animal use proposals and protocols Evaluation for compliance with USAMRDC and DOD Policies and other applicable standards Reporting of USAMRDC animal use Site visits to institutions receiving USAMRMC support and funding USAMRDC and the Department of Defense animal use policy applies to any live vertebrate animal, which is being used or is intended for use in a DOD animal care and use … Review Research Expenses on My Research On-line, How to Access & Understand Research Reports, Including RIS, Roles & Responsibilities in Accountability, Compliance & Spending, Annual Administrative Accountability Report. wildlife studies). As of 26 Nov 2018, Study Administrators can now initiate new forms on behalf of study PIs.. Summarize in narrative form the procedures and manipulations to be performed using animals, and explain why they are performed. Once approved by the IACUC and subsequently funded by the granting agency, the protocol becomes a public document. c. The original or revised protocol is then distributed to all IACUC members for review. Radio Options- Did you find this useful? A U of T AUP is also required in the following circumstances. Animal Use Protocol (AUP) (Application form Instructions) 1.Please refer to the NTU-IACUC Policies for Special Procedures before submitting this application. 4 Rationale 6 Procedures 8 Alternative Search 20 Procedure Relationships 21 Husbandry 22 Animal Disposition 25 Certifications 26. Research Oversight & Compliance Office (ROCO). The following guidance is offered to assist you in completing an Animal Use Protocol (AUP). UO policy. Animal Use Protocols Overview. Animals cannot be ordered or used at Davidson College until a protocol is approved by the Davidson College IACUC. the Principal Investigator (PI) can authorize certain personnel to initiate a protocol, but it is always submitted in the PI’s name. This lead time is required because protocols frequently require revisions before they can be submitted to the full membership of the IACUC for review. Training - Anyone working with animals must complete the related training and forms through online CITI Training courses. During your next amendment or continuing (deNovo) review submission, the updated form will ask you to re-enter … Animals, usually mice, are needed to produce these monoclonal antibody producing cells. Overview Any instructor or Principal Investigator (PI) working with vertebrate species or cephalopods must submit an animal use protocol (AUP) to the appropriate Local Animal Care Committee (LACC) through the online system – My Research Animal Protocol (MRAP). In order to comply with these guidelines and the requirements of the Animal Welfare Regulations (AWR), the Institutional Animal Care and Use Committee (IACUC) will review all protocols annually through the use of a Continuing (Annual) Review form and will require a new protocol submission every three years. e. The protocol is voted upon by the full Committee. Initial screening is performed by the IACUC chair, and the staff of the IACUC and AWS. Procedure. For assistance with any part of this process, please contact Courtney Reeks (613-562 … Florida Atlantic UniversityInstitutional Animal Care and Use Committee5/10 VersionRODENT BREEDING PROTOCOL FORMINSTRUCTIONS:Please complete all sections of this form. What ????? Animal Use Protocols All animal care and use (research, teaching, and testing) must be reviewed and approved by the Animal Care Committee prior to starting a research project. 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